Searchable abstracts of presentations at key conferences in endocrinology

ea0023oc3.5 | Oral Communications 3 | BSPED2009

Pituitary function at least 4 years after traumatic brain injury in childhood

Moon Rebecca , Sutton Timothy , Wilson Peter , Kirkham Fenella , Davies Justin

Introduction: Post-traumatic hypopituitarism (PTHP) is a recognised sequel of traumatic brain injury (TBI), occurring in 25–69% of adult patients, but there are few data on the prevalence or natural history in childhood. Our aim was to determine pituitary function in children at least 4 years after TBI requiring paediatric intensive care unit (PICU) admission. At the same time body composition was evaluated.Methods: Children discharged from the regi...

ea0015p18 | Bone | SFEBES2008

Expression and function of gut hormone receptors in osteoblast cell lines

Pacheco-Pantoja Elda , Wilson Peter , Ranganath Lakshminarayan , James Gallagher , Fraser William

The gastro-entero-pancreatic hormones are involved in the regulation of postprandial nutrient homeostasis. Food intake or fasting triggers the release of these hormones. A direct connection between food intake and bone turnover, assessed by biochemical markers of bone resorption and formation, has been demonstrated in animals and humans.The aim was to study the expression of receptors for the gut hormones, glucose-dependent insulinotropic polypeptide (GI...

ea0077lb57 | Late Breaking | SFEBES2021

A Novel LC-MS/MS Method for the Simultaneous Detection of Multiple Steroids in Plasma and Tissue Lysates, used to verify Cell Autonomous Sex Identity in birds

Denham Scott , Betterton Victoria , Ioannidis Jason , Lee Patricia , Zhao Debiao , Simpson Joanna , Caughey Sarah , Dunn Ian , Clinton Mike , Wilson Peter , Homer Natalie

Cell autonomous sex identity (CASI) of birds is the concept that sex-steroids have little or no effect on the development of secondary sexual characteristics in birds, and that sexual dimorphisms are determined by the sex-chromosome content of cells in individual tissues. In avian species males have a ZZ sex chromosome, while females are ZW. Sexual dimorphisms in chickens, such as muscle mass, comb and wattle size and hackles and spur development are believed to be determined ...